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Pharmacies Guide Updated: 2026-10-27 • 7 min read

Clavamox for Dogs & Cats Cost: Amoxicillin Clavulanate Prices

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Medically Reviewed & Price Audited Verified against FDA Center for Veterinary Medicine databases and licensed US pet pharmacies.

Essential Pricing Takeaways

  • • Clavamox (amoxicillin trihydrate + clavulanate potassium) by Zoetis is the premier broad-spectrum antibiotic for canine and feline bacterial skin, periodontal, and urinary tract infections.
  • • Brand Clavamox tablets cost $1.30 to $2.40 per tablet at veterinary hospital desks, while FDA-approved generic amoxicillin clavulanate costs only $0.45 to $0.85 per tablet at Chewy and Walmart PetRx.
  • • Liquid Clavamox drops for cats and puppies must be reconstituted with sterile water and refrigerated, expiring strictly after 10 days to maintain antibacterial potency.

Whether your dog developed an infected abscess from outdoor play, an acute bacterial hotspot, periodontal bone infection, or your cat is struggling with bacterial cystitis, Clavamox is typically the first-line oral antibiotic veterinarians prescribe. The addition of clavulanic acid protects amoxicillin from degradation by beta-lactamase enzymes produced by resistant staph bacteria.

However, animal hospitals often charge a high minimum dispensing fee plus substantial retail markup per pill. In this 2026 price guide, we show you how to save up to 65% by ordering generic amoxicillin clavulanate tablets or pediatric drops through accredited pet dispensaries.

2026 Brand Clavamox vs. Generic Amoxicillin Clavulanate Price Audit

Medication Form & StrengthQuantity / VolumeVet Clinic Counter PriceChewy PharmacyWalmart PetRx (Generic)Best Value Strategy Action
Clavamox Oral Drops (62.5mg/mL) Amoxicillin + Clavulanate Liquid 15mL Reconstituted Dropper $24.99 $22.50 Essential for cats and tiny puppies unable to swallow pills; discard after 10 days Check Price →
Generic Amox-Clav 62.5mg Tablets Amoxicillin 50mg + Clavulanate 12.5mg Foil-Wrapped Tablets (30ct) $21.99 $18.50 Foil strip packaging preserves moisture-sensitive clavulanic acid potency Check Price →
Generic Amox-Clav 125mg Tablets Amoxicillin 100mg + Clavulanate 25mg Foil-Wrapped Tablets (30ct) $26.99 $23.00 Save over 55% compared to private veterinary hospital pill charges Check Price →
Generic Amox-Clav 250mg Tablets Amoxicillin 200mg + Clavulanate 50mg Foil-Wrapped Tablets (30ct) $34.99 $29.50 Most prescribed strength for canine dental infections and deep wound flushes Check Price →
Generic Amox-Clav 375mg Tablets Amoxicillin 300mg + Clavulanate 75mg Foil-Wrapped Tablets (30ct) $44.99 $38.00 Two-week course costs under $40 online vs over $100 in-clinic Check Price →

*Pricing figures are audited periodically. Destination pharmacies may alter promotions or manufacturer rebates without advance notice.

Top Recommended Options & Discounts

Lowest Antibiotic Price ★ 4.9 / 5.0

Generic Amoxicillin Clavulanate Tablets

Best For: Dogs and cats needing broad-spectrum antibacterial therapy at 60% savings

Estimated Pharmacy Price: $18.50 - $38.00 per 30 tablets • Rx Prescription Required
  • ✓ FDA-approved generic equivalent manufactured by licensed laboratories (Norbrook / Lupin)
  • ✓ Identical active amoxicillin trihydrate and clavulanate potassium molecules
  • ✓ Foil blister packaging protects tablets from atmospheric humidity breakdown
Buy Generic at Walmart PetRx →
Classic Zoetis Brand ★ 4.8 / 5.0

Brand Clavamox Tablets (Zoetis)

Best For: Pet owners who prefer brand-name veterinary pharmaceuticals

Estimated Pharmacy Price: $26.99 - $54.99 per 30 tablets • Rx Prescription Required
  • ✓ Over 35 years of gold-standard veterinary clinical data and safety records
  • ✓ Film-coated tablets designed for easy swallowing with pill pockets
  • ✓ Available on Chewy Pharmacy with fast 1-to-2 day delivery
Shop Brand Clavamox on Chewy →
Virtual Infection Triage ★ 4.8 / 5.0

Dutch Online Vet Antibiotic Triage

Best For: Pet parents needing vet review for skin redness, wounds, or urinary symptoms

Estimated Pharmacy Price: $35.00 consultation fee • Over-The-Counter (No Rx)
  • ✓ Licensed video vet consults evaluate canine and feline bacterial infections
  • ✓ Direct digital prescription transfer to accredited online pet pharmacies
  • ✓ Same-day chat and video availability 7 days a week
Consult a Vet on Dutch →
Clinical Weight-to-Dose & Cost Calculator

Calculate Exact Dose & Cost-Per-Day by Pet Weight

Adjust the weight slider to determine the required clinical dose tier, monthly supply costs, and annual mail-order savings.

lbs
Toy (5 lbs)Small (20 lbs)Medium (45 lbs)Large (75 lbs)Giant (110+ lbs)
Prescribed Strength / Package Tier Simparica Trio for Dogs 44.1 - 88.0 lbs (Green Box)
FDA Approved Tier
Typical Vet Clinic Price:$38.00 / dose
Accredited Mail-Order:$21.50 / dose
Daily Treatment Cost:$0.72 / day
Estimated Annual Savings Save $198.00 / year (Up to 43% below clinic counter retail)
Check Price on 44-88 lb Dose →

*Prices audited across licensed dispensaries. Direct electronic prescription transfer supported.

Need a veterinary prescription for your pet's weight? Online vets can consult and authorize digital prescriptions in 15 minutes.
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How Clavulanic Acid Overcomes Beta-Lactamase Resistance

Amoxicillin is a semi-synthetic aminopenicillin that kills bacteria by inhibiting bacterial cell wall peptidoglycan synthesis. However, many common veterinary pathogens (notably Staphylococcus pseudintermedius) produce beta-lactamase enzymes that hydrolyze the penicillin ring, rendering amoxicillin ineffective.

Clavulanate potassium acts as a irreversible competitive "suicide" inhibitor of beta-lactamase enzymes. By binding tightly to the bacterial enzyme, it shields amoxicillin from degradation, extending its antibacterial killing spectrum against both Gram-positive and Gram-negative aerobic and anaerobic organisms.

Liquid Drops vs. Foil-Wrapped Tablets: Storage and Expiration

Clavulanic acid is extraordinarily sensitive to moisture and heat. Brand Clavamox and generic tablets are packaged in individual sealed aluminum foil blister packs. Never peel open tablets ahead of time or store them loose in plastic pill organizers, as moisture will rapidly degrade the clavulanate component.

For feline patients and small puppies, Clavamox is supplied as a dry powder in 15mL dropper bottles. Once reconstituted with sterile water at the pharmacy, the oral suspension must be kept strictly refrigerated and discarded after exactly 10 days, regardless of how much liquid remains in the bottle.

Preventing Antibiotic-Associated Diarrhea with Probiotics

Because Clavamox is a potent broad-spectrum antibiotic, it eliminates beneficial intestinal microflora alongside pathogenic bacteria, frequently inducing soft stool, vomiting, or diarrhea during treatment.

Veterinarians strongly recommend administering a targeted companion probiotic such as Purina Pro Plan FortiFlora or Nutramax Proviable during antibiotic courses. To prevent the antibiotic from killing the live probiotic bacteria, space probiotic administration at least 2 hours apart from your Clavamox dose.

Frequently Asked Questions

Can I give my dog human Augmentin instead of Clavamox? ↓
While Augmentin contains amoxicillin and clavulanate, human tablet ratios (e.g., 7:1 or 14:1) differ significantly from the 4:1 ratio calibrated for canine and feline metabolism. Human formulations can cause severe gastrointestinal distress.
Does Clavamox liquid need to be refrigerated? ↓
Yes! Reconstituted Clavamox liquid drops must be stored in the refrigerator (36°F to 46°F) and discarded after 10 days. Foil-wrapped tablets can be stored at controlled room temperature.
Why must Clavamox tablets stay in their foil blister packs? ↓
Clavulanate potassium is highly hygroscopic; exposure to atmospheric humidity causes rapid hydrolysis and loss of antibacterial efficacy. Only pop tablets from foil immediately before feeding.
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Veterinary Medical Reminder: Prescription pet medications require authorization from a licensed veterinarian with a valid Veterinary-Client-Patient Relationship (VCPR). Never administer prescription medications without veterinarian guidance. Outbound links connect to licensed US pet dispensaries.
Lowest Antibiotic Price
$18.50 - $38.00 per 30 tablets Generic Amoxicillin Clavulanate Tablets
Buy Generic at Walmart PetRx